| Symbol: Name: ID: |
ATG7 ATG7 autophagy related 7 homolog (S. cerevisiae) GFS:6023 |
| Gene name: | ATG7 |
| Chromosome: | 3p25.3-p25.2 |
| Previous Symbols: | APG7L |
| Previous Names: | APG7 autophagy 7-like (S. cerevisiae) |
| Aliases: | GSA7, DKFZp434N0735 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1921494 | Rat Genome Database ID: | RGD:1304817 |
| HGNC ID: | HGNC:16935 | RefSeq IDs: | NM_001136031 |
| Entrez Gene ID: | 10533 | Ensembl Gene ID: | ENSG00000197548 |
| VEGA IDs: | OTTHUMG00000129740 | UniProt ID: | O95352 |
| UCSC ID: | uc003bwc.2 | OMIM ID: | 608760 |
| Pubmed: | PMID10233149 | ||
| CCDS IDs: | CCDSCCDS2605.1 CCDS CCDS46752.1 CCDS CCDS46753.1 | ||
Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene.
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. [provided by RefSeq, Jan 2009].
Function: Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3 (By similarity).
Products for ATG7 gene
| Catalog | Product Name | Application | Company |
| GFS:E06023 | ATG7 autophagy related 7 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
| GFS:A06023 | ATG7 autophagy related 7 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
| GFS:P06023 | ATG7 autophagy related 7 homolog (S. cerevisiae); Protien | Protien | n/a |
