| Symbol: Name: ID: |
VAV2 vav 2 guanine nucleotide exchange factor GFS:2437 |
| Gene name: | VAV2 |
| Chromosome: | 9q34.1 |
| Previous Symbols: | |
| Previous Names: | vav 2 oncogene |
| Aliases: | |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:102718 | Rat Genome Database ID: | RGD:1306285 |
| HGNC ID: | HGNC:12658 | RefSeq IDs: | NM_001134398 |
| Entrez Gene ID: | 7410 | Ensembl Gene ID: | ENSG00000160293 |
| VEGA IDs: | OTTHUMG00000020882 | UniProt ID: | P52735 |
| UCSC ID: | uc004ces.2 | OMIM ID: | 600428 |
| Pubmed: | PMID7762982 | ||
| CCDS IDs: | CCDSCCDS6979.1 CCDS CCDS48053.1 | ||
Guanine nucleotide exchange factor VAV2 is a protein that in humans is encoded by the VAV2 gene.
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Function: Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).
Products for VAV2 gene
| Catalog | Product Name | Application | Company |
| GFS:E02437 | vav 2 guanine nucleotide exchange factor; ELISA kit | ELISA | n/a |
| GFS:A02437 | vav 2 guanine nucleotide exchange factor; Anti | ANTIBODIES | n/a |
| GFS:P02437 | vav 2 guanine nucleotide exchange factor; Protien | Protien | n/a |
