Symbol: Name: ID: |
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 GFS:6341 |
Gene name: | TNFAIP8 |
Chromosome: | 5q23.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | GG2-1, MDC-3.13, SCC-S2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2147191 | Rat Genome Database ID: | RGD:1305908 |
HGNC ID: | HGNC:17260 | RefSeq IDs: | NM_001077654 |
Entrez Gene ID: | 25816 | Ensembl Gene ID: | ENSG00000145779 |
VEGA IDs: | UniProt ID: | O95379 | |
UCSC ID: | uc003ksi.2 | OMIM ID: | 612111 |
Pubmed: | PMID10233894 PMID 10644768 | ||
CCDS IDs: | CCDSCCDS47257.1 CCDS CCDS47258.1 |
Tumor necrosis factor, alpha-induced protein 8 is a protein that in humans is encoded by the TNFAIP8 gene.
Function: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Products for TNFAIP8 gene
Catalog | Product Name | Application | Company |
GFS:E06341 | tumor necrosis factor, alpha-induced protein 8; ELISA kit | ELISA | n/a |
GFS:A06341 | tumor necrosis factor, alpha-induced protein 8; Anti | ANTIBODIES | n/a |
GFS:P06341 | tumor necrosis factor, alpha-induced protein 8; Protien | Protien | n/a |