Symbol: Name: ID: |
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) GFS:1709 |
Gene name: | TNFAIP1 |
Chromosome: | 17q22-q23 |
Previous Symbols: | EDP1 |
Previous Names: | |
Aliases: | B61, B12, MGC2317 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104961 | Rat Genome Database ID: | RGD:3877 |
HGNC ID: | HGNC:11894 | RefSeq IDs: | NM_021137 |
Entrez Gene ID: | 7126 | Ensembl Gene ID: | ENSG00000109079 |
VEGA IDs: | OTTHUMG00000132501 | UniProt ID: | Q13829 |
UCSC ID: | uc002hay.2 | OMIM ID: | 191161 |
Pubmed: | PMID2406243 PMID 2233719 | ||
CCDS IDs: | CCDSCCDS11227.1 |
BTB/POZ domain-containing protein TNFAIP1 is a protein that in humans is encoded by the TNFAIP1 gene. This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Products for TNFAIP1 gene
Catalog | Product Name | Application | Company |
GFS:E01709 | tumor necrosis factor, alpha-induced protein 1 (endothelial); ELISA kit | ELISA | n/a |
GFS:A01709 | tumor necrosis factor, alpha-induced protein 1 (endothelial); Anti | ANTIBODIES | n/a |
GFS:P01709 | tumor necrosis factor, alpha-induced protein 1 (endothelial); Protien | Protien | n/a |