Symbol: Name: ID: |
TFF3 trefoil factor 3 (intestinal) GFS:1574 |
Gene name: | TFF3 |
Chromosome: | 21q22.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HITF, ITF |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104638 | Rat Genome Database ID: | RGD:3847 |
HGNC ID: | HGNC:11757 | RefSeq IDs: | NM_003226 |
Entrez Gene ID: | 7033 | Ensembl Gene ID: | ENSG00000160180 |
VEGA IDs: | OTTHUMG00000086798 | UniProt ID: | Q07654 |
UCSC ID: | uc002zav.2 | OMIM ID: | 600633 |
Pubmed: | PMID7718582 PMID 9043862 | ||
CCDS IDs: | CCDSCCDS33565.1 |
Trefoil factor 3 is a protein that in humans is encoded by the TFF3 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
Products for TFF3 gene
Catalog | Product Name | Application | Company |
GFS:E01574 | trefoil factor 3 (intestinal); ELISA kit | ELISA | n/a |
GFS:A01574 | trefoil factor 3 (intestinal); Anti | ANTIBODIES | n/a |
GFS:P01574 | trefoil factor 3 (intestinal); Protien | Protien | n/a |