Symbol: Name: ID: |
TFF1 trefoil factor 1 GFS:1572 |
Gene name: | TFF1 |
Chromosome: | 21q22.3 |
Previous Symbols: | BCEI |
Previous Names: | breast cancer, estrogen-inducible sequence expressed in |
Aliases: | D21S21, HPS2, pS2, pNR-2, HP1.A |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88135 | Rat Genome Database ID: | RGD:620707 |
HGNC ID: | HGNC:11755 | RefSeq IDs: | NM_003225 |
Entrez Gene ID: | 7031 | Ensembl Gene ID: | ENSG00000160182 |
VEGA IDs: | OTTHUMG00000086799 | UniProt ID: | P04155 |
UCSC ID: | uc002zax.1 | OMIM ID: | 113710 |
Pubmed: | PMID9043862 | ||
CCDS IDs: | CCDSCCDS13685.1 |
Trefoil factor 1 is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
Products for TFF1 gene
Catalog | Product Name | Application | Company |
GFS:E01572 | trefoil factor 1; ELISA kit | ELISA | n/a |
GFS:A01572 | trefoil factor 1; Anti | ANTIBODIES | n/a |
GFS:P01572 | trefoil factor 1; Protien | Protien | n/a |