Symbol: Name: ID: |
TFF2 trefoil factor 2 GFS:1573 |
Gene name: | TFF2 |
Chromosome: | 21q22.3 |
Previous Symbols: | SML1 |
Previous Names: | spasmolytic protein 1 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1306805 | Rat Genome Database ID: | RGD:620709 |
HGNC ID: | HGNC:11756 | RefSeq IDs: | NM_005423 |
Entrez Gene ID: | 7032 | Ensembl Gene ID: | ENSG00000160181 |
VEGA IDs: | OTTHUMG00000086797 | UniProt ID: | Q03403 |
UCSC ID: | uc002zaw.2 | OMIM ID: | 182590 |
Pubmed: | PMID1505966 PMID 9043862 | ||
CCDS IDs: | CCDSCCDS13684.1 |
Trefoil factor 2 is a protein that in humans is encoded by the TFF2 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).
Products for TFF2 gene
Catalog | Product Name | Application | Company |
GFS:E01573 | trefoil factor 2; ELISA kit | ELISA | n/a |
GFS:A01573 | trefoil factor 2; Anti | ANTIBODIES | n/a |
GFS:P01573 | trefoil factor 2; Protien | Protien | n/a |