Symbol: Name: ID: |
TMPRSS6 transmembrane protease, serine 6 GFS:5623 |
Gene name: | TMPRSS6 |
Chromosome: | 22q13.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FLJ30744 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919003 | Rat Genome Database ID: | RGD:1307138 |
HGNC ID: | HGNC:16517 | RefSeq IDs: | NM_153609 |
Entrez Gene ID: | 164656 | Ensembl Gene ID: | ENSG00000187045 |
VEGA IDs: | OTTHUMG00000150541 | UniProt ID: | Q8IU80 |
UCSC ID: | uc003aqs.1 | OMIM ID: | 609862 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS13941.1 |
Transmembrane protease, serine 6 is an enzyme that in humans is encoded by the TMPRSS6 gene.
The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Required to sense iron deficiency. Overexpression suppresses activation of the HAMP promoter.
Products for TMPRSS6 gene
Catalog | Product Name | Application | Company |
GFS:E05623 | transmembrane protease, serine 6; ELISA kit | ELISA | n/a |
GFS:A05623 | transmembrane protease, serine 6; Anti | ANTIBODIES | n/a |
GFS:P05623 | transmembrane protease, serine 6; Protien | Protien | n/a |