Symbol: Name: ID: |
TRPV1 transient receptor potential cation channel, subfamily V, member 1 GFS:2485 |
Gene name: | TRPV1 |
Chromosome: | 17p13.3 |
Previous Symbols: | VR1 |
Previous Names: | vanilloid receptor subtype 1 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1341787 | Rat Genome Database ID: | RGD:628841 |
HGNC ID: | HGNC:12716 | RefSeq IDs: | NM_018727 |
Entrez Gene ID: | 7442 | Ensembl Gene ID: | ENSG00000196689 |
VEGA IDs: | UniProt ID: | Q8NER1 | |
UCSC ID: | uc010vrt.1 | OMIM ID: | 602076 |
Pubmed: | PMID9349813 PMID 11549313 PMID 16382100 | ||
CCDS IDs: | CCDSCCDS45576.1 |
The transient receptor potential cation channel subfamily V member 1 (TrpV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene. It was the first isolated member of the transient receptor potential vanilloid receptor proteins which in turn are a sub family of the transient receptor potential protein group. This protein is a member of the TRPV group of transient receptor potential family of ion channels.
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq].
Products for TRPV1 gene
Catalog | Product Name | Application | Company |
GFS:E02485 | transient receptor potential cation channel, subfamily V, member 1; ELISA kit | ELISA | n/a |
GFS:A02485 | transient receptor potential cation channel, subfamily V, member 1; Anti | ANTIBODIES | n/a |
GFS:P02485 | transient receptor potential cation channel, subfamily V, member 1; Protien | Protien | n/a |