Symbol: Name: ID: |
TRPC5 transient receptor potential cation channel, subfamily C, member 5 GFS:2149 |
Gene name: | TRPC5 |
Chromosome: | Xq23 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109524 | Rat Genome Database ID: | RGD:619787 |
HGNC ID: | HGNC:12337 | RefSeq IDs: | NM_012471 |
Entrez Gene ID: | 7224 | Ensembl Gene ID: | ENSG00000072315 |
VEGA IDs: | OTTHUMG00000022212 | UniProt ID: | Q9UL62 |
UCSC ID: | uc004epl.1 | OMIM ID: | 300334 |
Pubmed: | PMID10493832 PMID 16382100 | ||
CCDS IDs: | CCDSCCDS14561.1 |
Short transient receptor potential channel 5 (TrpC5) also known as transient receptor protein 5 (TRP-5) is a protein that in humans is encoded by the TRPC5 gene. This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion.
Products for TRPC5 gene
Catalog | Product Name | Application | Company |
GFS:E02149 | transient receptor potential cation channel, subfamily C, member 5; ELISA kit | ELISA | n/a |
GFS:A02149 | transient receptor potential cation channel, subfamily C, member 5; Anti | ANTIBODIES | n/a |
GFS:P02149 | transient receptor potential cation channel, subfamily C, member 5; Protien | Protien | n/a |