Symbol: Name: ID: |
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein GFS:5308 |
Gene name: | TRPC4AP |
Chromosome: | 20q11.23 |
Previous Symbols: | C20orf188 |
Previous Names: | chromosome 20 open reading frame 188 |
Aliases: | DKFZP727M231, DKFZp586C1223, dJ756N5.2, TRRP4AP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1930751 | Rat Genome Database ID: | RGD:1309914 |
HGNC ID: | HGNC:16181 | RefSeq IDs: | NM_015638 |
Entrez Gene ID: | 26133 | Ensembl Gene ID: | ENSG00000100991 |
VEGA IDs: | OTTHUMG00000032319 | UniProt ID: | Q8TEL6 |
UCSC ID: | uc002xbk.2 | OMIM ID: | 608430 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS13246.1 CCDS CCDS46591.1 |
Trpc4-associated protein is a protein that in humans is encoded by the TRPC4AP gene.
Function: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
Products for TRPC4AP gene
Catalog | Product Name | Application | Company |
GFS:E05308 | transient receptor potential cation channel, subfamily C, member 4 associated protein; ELISA kit | ELISA | n/a |
GFS:A05308 | transient receptor potential cation channel, subfamily C, member 4 associated protein; Anti | ANTIBODIES | n/a |
GFS:P05308 | transient receptor potential cation channel, subfamily C, member 4 associated protein; Protien | Protien | n/a |