Symbol: Name: ID: |
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) GFS:1563 |
Gene name: | TFAP2C |
Chromosome: | 20q13.2 |
Previous Symbols: | |
Previous Names: | transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma) |
Aliases: | AP2-GAMMA, ERF1, TFAP2G, hAP-2g |
Name Aliases: | estrogen receptor factor 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106032 | Rat Genome Database ID: | RGD:1303185 |
HGNC ID: | HGNC:11744 | RefSeq IDs: | NM_003222 |
Entrez Gene ID: | 7022 | Ensembl Gene ID: | ENSG00000087510 |
VEGA IDs: | OTTHUMG00000032805 | UniProt ID: | Q92754 |
UCSC ID: | uc002xya.2 | OMIM ID: | 601602 |
Pubmed: | PMID8661133 | ||
CCDS IDs: | CCDSCCDS13454.1 |
The protein encoded by TFAP2C is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Products for TFAP2C gene
Catalog | Product Name | Application | Company |
GFS:E01563 | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); ELISA kit | ELISA | n/a |
GFS:A01563 | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); Anti | ANTIBODIES | n/a |
GFS:P01563 | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); Protien | Protien | n/a |