Symbol: Name: ID: |
TRIP6 thyroid hormone receptor interactor 6 GFS:2127 |
Gene name: | TRIP6 |
Chromosome: | 7q22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | ZRP-1, OIP1, MGC10556, MGC10558, MGC29959, MGC3837, MGC4423 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1343458 | Rat Genome Database ID: | |
HGNC ID: | HGNC:12311 | RefSeq IDs: | NM_003302 |
Entrez Gene ID: | 7205 | Ensembl Gene ID: | ENSG00000087077 |
VEGA IDs: | OTTHUMG00000157029 | UniProt ID: | Q15654 |
UCSC ID: | uc003uww.2 | OMIM ID: | 602933 |
Pubmed: | PMID9598321 PMID 7776974 | ||
CCDS IDs: | CCDSCCDS5708.1 |
Thyroid receptor-interacting protein 6 is a protein that in humans is encoded by the TRIP6 gene. This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. (provided by RefSeq) .
Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor
Products for TRIP6 gene
Catalog | Product Name | Application | Company |
GFS:E02127 | thyroid hormone receptor interactor 6; ELISA kit | ELISA | n/a |
GFS:A02127 | thyroid hormone receptor interactor 6; Anti | ANTIBODIES | n/a |
GFS:P02127 | thyroid hormone receptor interactor 6; Protien | Protien | n/a |