Symbol: Name: ID: |
TRIP12 thyroid hormone receptor interactor 12 GFS:2123 |
Gene name: | TRIP12 |
Chromosome: | 2q36.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0045 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1309481 | Rat Genome Database ID: | RGD:1306607 |
HGNC ID: | HGNC:12306 | RefSeq IDs: | NM_004238 |
Entrez Gene ID: | 9320 | Ensembl Gene ID: | ENSG00000153827 |
VEGA IDs: | OTTHUMG00000153623 | UniProt ID: | Q14669 |
UCSC ID: | uc002vpw.1 | OMIM ID: | 604506 |
Pubmed: | PMID7776974 | ||
CCDS IDs: | CCDSCCDS33391.1 |
Probable E3 ubiquitin-protein ligase TRIP12 is an enzyme that in humans is encoded by the TRIP12 gene. Component of PA700, an ATP-dependent multisubunit protein that activates the proteolytic activities of the multifunctional proteinase (20S proteasome) of the 26S complex. Specifically interacts with the ligand binding domain of the thyroid hormone receptor (in a thyroid hormone T3-independent manner) and with retinoid X receptor (RXR). Could be E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Products for TRIP12 gene
Catalog | Product Name | Application | Company |
GFS:E02123 | thyroid hormone receptor interactor 12; ELISA kit | ELISA | n/a |
GFS:A02123 | thyroid hormone receptor interactor 12; Anti | ANTIBODIES | n/a |
GFS:P02123 | thyroid hormone receptor interactor 12; Protien | Protien | n/a |