Symbol: Name: ID: |
TAS2R8 taste receptor, type 2, member 8 GFS:4203 |
Gene name: | TAS2R8 |
Chromosome: | 12p13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | T2R8, TRB5 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:14915 | RefSeq IDs: | NM_023918 |
Entrez Gene ID: | 50836 | Ensembl Gene ID: | ENSG00000121314 |
VEGA IDs: | OTTHUMG00000134536 | UniProt ID: | Q9NYW2 |
UCSC ID: | uc010shh.1 | OMIM ID: | 604794 |
Pubmed: | PMID10761934 PMID 10766242 | ||
CCDS IDs: | CCDSCCDS8632.1 |
Taste receptor type 2 member 8 is a protein that in humans is encoded by the TAS2R8 gene.
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008].
Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Products for TAS2R8 gene
Catalog | Product Name | Application | Company |
GFS:E04203 | taste receptor, type 2, member 8; ELISA kit | ELISA | n/a |
GFS:A04203 | taste receptor, type 2, member 8; Anti | ANTIBODIES | n/a |
GFS:P04203 | taste receptor, type 2, member 8; Protien | Protien | n/a |