Symbol: Name: ID: |
TAS2R4 taste receptor, type 2, member 4 GFS:4199 |
Gene name: | TAS2R4 |
Chromosome: | 7q31.3-q32 |
Previous Symbols: | |
Previous Names: | |
Aliases: | T2R4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2681210 | Rat Genome Database ID: | RGD:1561194 |
HGNC ID: | HGNC:14911 | RefSeq IDs: | NM_016944 |
Entrez Gene ID: | 50832 | Ensembl Gene ID: | ENSG00000127364 |
VEGA IDs: | OTTHUMG00000157634 | UniProt ID: | Q9NYW5 |
UCSC ID: | uc003vwq.1 | OMIM ID: | 604869 |
Pubmed: | PMID10761934 PMID 10761935 | ||
CCDS IDs: | CCDSCCDS5868.1 |
Taste receptor type 2 member 4 is a protein that in humans is encoded by the TAS2R4 gene.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
Products for TAS2R4 gene
Catalog | Product Name | Application | Company |
GFS:E04199 | taste receptor, type 2, member 4; ELISA kit | ELISA | n/a |
GFS:A04199 | taste receptor, type 2, member 4; Anti | ANTIBODIES | n/a |
GFS:P04199 | taste receptor, type 2, member 4; Protien | Protien | n/a |