Symbol: Name: ID: |
TAS2R43 taste receptor, type 2, member 43 GFS:7696 |
Gene name: | TAS2R43 |
Chromosome: | 12p13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | T2R52 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:18875 | RefSeq IDs: | NM_176884 |
Entrez Gene ID: | 259289 | Ensembl Gene ID: | ENSG00000255374 |
VEGA IDs: | OTTHUMG00000134559 | UniProt ID: | P59537 |
UCSC ID: | uc001qzq.1 | OMIM ID: | 612668 |
Pubmed: | PMID12379855 | ||
CCDS IDs: |
Taste receptor type 2 member 43 is a protein that in humans is encoded by the TAS2R43 gene.
TAS2R43 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Mar 2009]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May acts as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
Products for TAS2R43 gene
Catalog | Product Name | Application | Company |
GFS:E07696 | taste receptor, type 2, member 43; ELISA kit | ELISA | n/a |
GFS:A07696 | taste receptor, type 2, member 43; Anti | ANTIBODIES | n/a |
GFS:P07696 | taste receptor, type 2, member 43; Protien | Protien | n/a |