Symbol: Name: ID: |
SYT12 synaptotagmin XII GFS:7245 |
Gene name: | SYT12 |
Chromosome: | 11q12.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SRG1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2159601 | Rat Genome Database ID: | RGD:621876 |
HGNC ID: | HGNC:18381 | RefSeq IDs: | NM_001177880 |
Entrez Gene ID: | 91683 | Ensembl Gene ID: | ENSG00000173227 |
VEGA IDs: | UniProt ID: | Q8IV01 | |
UCSC ID: | uc001oju.2 | OMIM ID: | 606436 |
Pubmed: | PMID8987811 | ||
CCDS IDs: | CCDSCCDS8154.1 |
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.[provided by RefSeq, Apr 2010].
Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity).
Products for SYT12 gene
Catalog | Product Name | Application | Company |
GFS:E07245 | synaptotagmin XII; ELISA kit | ELISA | n/a |
GFS:A07245 | synaptotagmin XII; Anti | ANTIBODIES | n/a |
GFS:P07245 | synaptotagmin XII; Protien | Protien | n/a |