Symbol: Name: ID: |
SNX17 sorting nexin 17 GFS:4260 |
Gene name: | SNX17 |
Chromosome: | 2p23-p22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0064 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2387801 | Rat Genome Database ID: | RGD:1306424 |
HGNC ID: | HGNC:14979 | RefSeq IDs: | NM_014748 |
Entrez Gene ID: | 9784 | Ensembl Gene ID: | ENSG00000115234 |
VEGA IDs: | OTTHUMG00000097781 | UniProt ID: | Q15036 |
UCSC ID: | uc002rkg.1 | OMIM ID: | 605963 |
Pubmed: | PMID12169628 PMID 15769472 | ||
CCDS IDs: | CCDSCCDS1750.1 |
Sorting nexin-17 is a protein that in humans is encoded by the SNX17 gene.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May be involved in several stages of intracellular protein trafficking. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Products for SNX17 gene
Catalog | Product Name | Application | Company |
GFS:E04260 | sorting nexin 17; ELISA kit | ELISA | n/a |
GFS:A04260 | sorting nexin 17; Anti | ANTIBODIES | n/a |
GFS:P04260 | sorting nexin 17; Protien | Protien | n/a |