Symbol: Name: ID: |
SOS1 son of sevenless homolog 1 (Drosophila) GFS:1086 |
Gene name: | SOS1 |
Chromosome: | 2p21 |
Previous Symbols: | GINGF |
Previous Names: | gingival fibromatosis, hereditary, 1 |
Aliases: | HGF, GF1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98354 | Rat Genome Database ID: | RGD:1310949 |
HGNC ID: | HGNC:11187 | RefSeq IDs: | NM_005633 |
Entrez Gene ID: | 6654 | Ensembl Gene ID: | ENSG00000115904 |
VEGA IDs: | OTTHUMG00000102109 | UniProt ID: | Q07889 |
UCSC ID: | uc002rrk.3 | OMIM ID: | 182530 |
Pubmed: | PMID8276400 PMID 10995566 | ||
CCDS IDs: | CCDSCCDS1802.1 |
Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene. This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SOS1 gene
Catalog | Product Name | Application | Company |
GFS:E01086 | son of sevenless homolog 1 (Drosophila); ELISA kit | ELISA | n/a |
GFS:A01086 | son of sevenless homolog 1 (Drosophila); Anti | ANTIBODIES | n/a |
GFS:P01086 | son of sevenless homolog 1 (Drosophila); Protien | Protien | n/a |