Symbol: Name: ID: |
SRP68 signal recognition particle 68kDa GFS:1194 |
Gene name: | SRP68 |
Chromosome: | 17q25.1 |
Previous Symbols: | |
Previous Names: | signal recognition particle 68kD |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1917447 | Rat Genome Database ID: | RGD:1305376 |
HGNC ID: | HGNC:11302 | RefSeq IDs: | NM_014230 |
Entrez Gene ID: | 6730 | Ensembl Gene ID: | ENSG00000167881 |
VEGA IDs: | OTTHUMG00000142277 | UniProt ID: | Q9UHB9 |
UCSC ID: | uc002jqk.1 | OMIM ID: | 604858 |
Pubmed: | PMID10618370 | ||
CCDS IDs: | CCDSCCDS11738.1 |
The signal recognition particle (SRP) is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. This gene encodes the 68kDa component of the SRP. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq].
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
Products for SRP68 gene
Catalog | Product Name | Application | Company |
GFS:E01194 | signal recognition particle 68kDa; ELISA kit | ELISA | n/a |
GFS:A01194 | signal recognition particle 68kDa; Anti | ANTIBODIES | n/a |
GFS:P01194 | signal recognition particle 68kDa; Protien | Protien | n/a |