Symbol: Name: ID: |
SSRP1 structure specific recognition protein 1 GFS:1216 |
Gene name: | SSRP1 |
Chromosome: | 11q12 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FACT80 |
Name Aliases: | facilitates chromatin remodeling 80 kDa subunit |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107912 | Rat Genome Database ID: | RGD:621143 |
HGNC ID: | HGNC:11327 | RefSeq IDs: | NM_003146 |
Entrez Gene ID: | 6749 | Ensembl Gene ID: | ENSG00000149136 |
VEGA IDs: | UniProt ID: | Q08945 | |
UCSC ID: | uc001njt.2 | OMIM ID: | 604328 |
Pubmed: | PMID1372440 | ||
CCDS IDs: | CCDSCCDS7952.1 |
Structure specific recognition protein 1, also known as SSRP1, is a human protein. The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SSRP1 gene
Catalog | Product Name | Application | Company |
GFS:E01216 | structure specific recognition protein 1; ELISA kit | ELISA | n/a |
GFS:A01216 | structure specific recognition protein 1; Anti | ANTIBODIES | n/a |
GFS:P01216 | structure specific recognition protein 1; Protien | Protien | n/a |