Symbol: Name: ID: |
PLA2G15 phospholipase A2, group XV GFS:6249 |
Gene name: | PLA2G15 |
Chromosome: | 16q22.1 |
Previous Symbols: | LYPLA3 |
Previous Names: | lysophospholipase 3 (lysosomal phospholipase A2) |
Aliases: | LLPL, GXVPLA2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2178076 | Rat Genome Database ID: | RGD:1302982 |
HGNC ID: | HGNC:17163 | RefSeq IDs: | NM_012320 |
Entrez Gene ID: | 23659 | Ensembl Gene ID: | ENSG00000103066 |
VEGA IDs: | OTTHUMG00000137554 | UniProt ID: | Q8NCC3 |
UCSC ID: | uc002evr.2 | OMIM ID: | 609362 |
Pubmed: | PMID10092508 PMID 16973413 | ||
CCDS IDs: | CCDSCCDS10864.1 |
Group XV phospholipase A2 is an enzyme that in humans is encoded by the PLA2G15 gene.
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N-acetylsphingosine and the concomitant release of a lyso-phospholipid (By similarity). May have weak lysophospholipase activity.
Products for PLA2G15 gene
Catalog | Product Name | Application | Company |
GFS:E06249 | phospholipase A2, group XV; ELISA kit | ELISA | n/a |
GFS:A06249 | phospholipase A2, group XV; Anti | ANTIBODIES | n/a |
GFS:P06249 | phospholipase A2, group XV; Protien | Protien | n/a |