Symbol: Name: ID: |
PLA2G12A phospholipase A2, group XIIA GFS:7399 |
Gene name: | PLA2G12A |
Chromosome: | 4q25 |
Previous Symbols: | PLA2G12 |
Previous Names: | phospholipase A2, group XII |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913600 | Rat Genome Database ID: | RGD:1304662 |
HGNC ID: | HGNC:18554 | RefSeq IDs: | NM_030821 |
Entrez Gene ID: | 81579 | Ensembl Gene ID: | ENSG00000123739 |
VEGA IDs: | OTTHUMG00000131915 | UniProt ID: | Q9BZM1 |
UCSC ID: | uc003hzp.2 | OMIM ID: | 611652 |
Pubmed: | PMID11031251 | ||
CCDS IDs: | CCDSCCDS3686.1 |
Group XIIA secretory phospholipase A2 is an enzyme that in humans is encoded by the PLA2G12A gene.
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM, Mar 2008]. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments.
Function: PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
Products for PLA2G12A gene
Catalog | Product Name | Application | Company |
GFS:E07399 | phospholipase A2, group XIIA; ELISA kit | ELISA | n/a |
GFS:A07399 | phospholipase A2, group XIIA; Anti | ANTIBODIES | n/a |
GFS:P07399 | phospholipase A2, group XIIA; Protien | Protien | n/a |