Symbol: Name: ID: |
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 GFS:5048 |
Gene name: | PAK7 |
Chromosome: | 20p12 |
Previous Symbols: | |
Previous Names: | p21(CDKN1A)-activated kinase 7 |
Aliases: | KIAA1264, PAK5 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1920334 | Rat Genome Database ID: | RGD:1312009 |
HGNC ID: | HGNC:15916 | RefSeq IDs: | NM_020341 |
Entrez Gene ID: | 57144 | Ensembl Gene ID: | ENSG00000101349 |
VEGA IDs: | OTTHUMG00000031857 | UniProt ID: | Q9P286 |
UCSC ID: | uc002wnk.2 | OMIM ID: | 608038 |
Pubmed: | PMID11756552 PMID 10574462 | ||
CCDS IDs: | CCDSCCDS13107.1 |
Serine/threonine-protein kinase PAK 7 is an enzyme that in humans is encoded by the PAK7 gene.
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
Function: The activated kinase acts on a variety of targets (By similarity).
Products for PAK7 gene
Catalog | Product Name | Application | Company |
GFS:E05048 | p21 protein (Cdc42/Rac)-activated kinase 7; ELISA kit | ELISA | n/a |
GFS:A05048 | p21 protein (Cdc42/Rac)-activated kinase 7; Anti | ANTIBODIES | n/a |
GFS:P05048 | p21 protein (Cdc42/Rac)-activated kinase 7; Protien | Protien | n/a |