Symbol: Name: ID: |
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 GFS:5187 |
Gene name: | PAK6 |
Chromosome: | 15q14 |
Previous Symbols: | |
Previous Names: | p21(CDKN1A)-activated kinase 6 |
Aliases: | PAK5 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2679420 | Rat Genome Database ID: | RGD:1306213 |
HGNC ID: | HGNC:16061 | RefSeq IDs: | NM_001128628 |
Entrez Gene ID: | 56924 | Ensembl Gene ID: | ENSG00000137843 |
VEGA IDs: | OTTHUMG00000129921 | UniProt ID: | Q9NQU5 |
UCSC ID: | uc010bbl.2 | OMIM ID: | 608110 |
Pubmed: | PMID11278661 | ||
CCDS IDs: | CCDSCCDS10054.1 |
Serine/threonine-protein kinase PAK 6 is an enzyme that in humans is encoded by the PAK6 gene.
This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Function: The activated kinase acts on a variety of targets (By similarity).
Products for PAK6 gene
Catalog | Product Name | Application | Company |
GFS:E05187 | p21 protein (Cdc42/Rac)-activated kinase 6; ELISA kit | ELISA | n/a |
GFS:A05187 | p21 protein (Cdc42/Rac)-activated kinase 6; Anti | ANTIBODIES | n/a |
GFS:P05187 | p21 protein (Cdc42/Rac)-activated kinase 6; Protien | Protien | n/a |