Symbol: Name: ID: |
MED12L mediator complex subunit 12-like GFS:5178 |
Gene name: | MED12L |
Chromosome: | 3q25.1 |
Previous Symbols: | |
Previous Names: | mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)-like |
Aliases: | KIAA1635, TNRC11L, TRALPUSH, TRALP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2139916 | Rat Genome Database ID: | |
HGNC ID: | HGNC:16050 | RefSeq IDs: | NM_053002 |
Entrez Gene ID: | 116931 | Ensembl Gene ID: | ENSG00000144893 |
VEGA IDs: | OTTHUMG00000159844 | UniProt ID: | Q86YW9 |
UCSC ID: | uc003eyp.2 | OMIM ID: | 611318 |
Pubmed: | PMID11524702 | ||
CCDS IDs: | CCDSCCDS33876.1 |
The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Function: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Products for MED12L gene
Catalog | Product Name | Application | Company |
GFS:E05178 | mediator complex subunit 12-like; ELISA kit | ELISA | n/a |
GFS:A05178 | mediator complex subunit 12-like; Anti | ANTIBODIES | n/a |
GFS:P05178 | mediator complex subunit 12-like; Protien | Protien | n/a |