Symbol: Name: ID: |
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) GFS:6088 |
Gene name: | TMED10 |
Chromosome: | 14q24.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | TMP21, P24(DELTA) |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1915831 | Rat Genome Database ID: | RGD:620970 |
HGNC ID: | HGNC:16998 | RefSeq IDs: | NM_006827 |
Entrez Gene ID: | 10972 | Ensembl Gene ID: | ENSG00000170348 |
VEGA IDs: | UniProt ID: | P49755 | |
UCSC ID: | uc001xrm.1 | OMIM ID: | 605406 |
Pubmed: | PMID7596406 PMID 8663407 | ||
CCDS IDs: | CCDSCCDS9840.1 |
Transmembrane emp24 domain-containing protein 10 is a protein that in humans is encoded by the TMED10 gene.
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Involved in vesicular protein trafficking.
Products for TMED10 gene
Catalog | Product Name | Application | Company |
GFS:E06088 | transmembrane emp24-like trafficking protein 10 (yeast); ELISA kit | ELISA | n/a |
GFS:A06088 | transmembrane emp24-like trafficking protein 10 (yeast); Anti | ANTIBODIES | n/a |
GFS:P06088 | transmembrane emp24-like trafficking protein 10 (yeast); Protien | Protien | n/a |