Symbol: Name: ID: |
KRTAP3-3 keratin associated protein 3-3 GFS:7707 |
Gene name: | KRTAP3-3 |
Chromosome: | 17q12-q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KAP3.3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913630 | Rat Genome Database ID: | RGD:1307504 |
HGNC ID: | HGNC:18890 | RefSeq IDs: | NM_033185 |
Entrez Gene ID: | 85293 | Ensembl Gene ID: | ENSG00000212899 |
VEGA IDs: | OTTHUMG00000133591 | UniProt ID: | Q9BYR6 |
UCSC ID: | uc002hvr.1 | OMIM ID: | |
Pubmed: | PMID11279113 | ||
CCDS IDs: | CCDSCCDS32643.1 |
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008].
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Products for KRTAP3-3 gene
Catalog | Product Name | Application | Company |
GFS:E07707 | keratin associated protein 3-3; ELISA kit | ELISA | n/a |
GFS:A07707 | keratin associated protein 3-3; Anti | ANTIBODIES | n/a |
GFS:P07707 | keratin associated protein 3-3; Protien | Protien | n/a |