Symbol: Name: ID: |
KRTAP2-4 keratin associated protein 2-4 GFS:7708 |
Gene name: | KRTAP2-4 |
Chromosome: | 17q12-q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KAP2.4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:18891 | RefSeq IDs: | NM_033184 |
Entrez Gene ID: | 85294 | Ensembl Gene ID: | ENSG00000213417 |
VEGA IDs: | OTTHUMG00000133594 | UniProt ID: | Q9BYR9 |
UCSC ID: | uc002hvx.2 | OMIM ID: | |
Pubmed: | PMID11279113 | ||
CCDS IDs: |
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. (provided by RefSeq)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Products for KRTAP2-4 gene
Catalog | Product Name | Application | Company |
GFS:E07708 | keratin associated protein 2-4; ELISA kit | ELISA | n/a |
GFS:A07708 | keratin associated protein 2-4; Anti | ANTIBODIES | n/a |
GFS:P07708 | keratin associated protein 2-4; Protien | Protien | n/a |