Symbol: Name: ID: |
KRTAP1-4 keratin associated protein 1-4 GFS:7719 |
Gene name: | KRTAP1-4 |
Chromosome: | 17q21.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KAP1.4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:18904 | RefSeq IDs: | XM_001127005 |
Entrez Gene ID: | 728255 | Ensembl Gene ID: | ENSG00000204887 |
VEGA IDs: | OTTHUMG00000133631 | UniProt ID: | P0C5Y4 |
UCSC ID: | OMIM ID: | 608821 | |
Pubmed: | |||
CCDS IDs: |
The main structural proteins of mammalian hair fiber are the hair keratins (see MIM 601077) and the keratin-associated proteins (KAPs), which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking with the abundant cysteines of hair keratins (Shimomura et al., 2002 (PubMed 12228244)).(supplied by OMIM)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Products for KRTAP1-4 gene
Catalog | Product Name | Application | Company |
GFS:E07719 | keratin associated protein 1-4; ELISA kit | ELISA | n/a |
GFS:A07719 | keratin associated protein 1-4; Anti | ANTIBODIES | n/a |
GFS:P07719 | keratin associated protein 1-4; Protien | Protien | n/a |