Symbol: Name: ID: |
EIF3L eukaryotic translation initiation factor 3, subunit L GFS:7025 |
Gene name: | EIF3L |
Chromosome: | 22q |
Previous Symbols: | EIF3S6IP, EIF3EIP |
Previous Names: | eukaryotic translation initiation factor 3, subunit 6 interacting protein, "eukaryotic translation initiation factor 3, subunit E interacting protein" |
Aliases: | HSPC021, HSPC025, EIF3S11 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2386251 | Rat Genome Database ID: | |
HGNC ID: | HGNC:18138 | RefSeq IDs: | NM_016091 |
Entrez Gene ID: | 51386 | Ensembl Gene ID: | ENSG00000100129 |
VEGA IDs: | OTTHUMG00000150671 | UniProt ID: | Q9Y262 |
UCSC ID: | uc003auf.2 | OMIM ID: | |
Pubmed: | PMID11042152 PMID 11590142 | ||
CCDS IDs: | CCDSCCDS13960.1 |
Eukaryotic translation initiation factor 3 subunit L is a protein that in humans is encoded by the EIF3L gene.
Function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Products for EIF3L gene
Catalog | Product Name | Application | Company |
GFS:E07025 | eukaryotic translation initiation factor 3, subunit L; ELISA kit | ELISA | n/a |
GFS:A07025 | eukaryotic translation initiation factor 3, subunit L; Anti | ANTIBODIES | n/a |
GFS:P07025 | eukaryotic translation initiation factor 3, subunit L; Protien | Protien | n/a |