Symbol: Name: ID: |
EIF2C4 eukaryotic translation initiation factor 2C, 4 GFS:7281 |
Gene name: | EIF2C4 |
Chromosome: | 1p34 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FLJ20033, AGO4, KIAA1567 |
Name Aliases: | argonaute 4 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1924100 | Rat Genome Database ID: | RGD:1304583 |
HGNC ID: | HGNC:18424 | RefSeq IDs: | NM_017629 |
Entrez Gene ID: | 192670 | Ensembl Gene ID: | ENSG00000134698 |
VEGA IDs: | OTTHUMG00000004243 | UniProt ID: | Q9HCK5 |
UCSC ID: | uc001bzj.1 | OMIM ID: | 607356 |
Pubmed: | PMID12906857 | ||
CCDS IDs: | CCDSCCDS397.1 |
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic containing PAZ and PIWI domains, and it may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and eukaryotic translation initiation factor 2C, 1. [provided by RefSeq, Jul 2008].
Function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).
Products for EIF2C4 gene
Catalog | Product Name | Application | Company |
GFS:E07281 | eukaryotic translation initiation factor 2C, 4; ELISA kit | ELISA | n/a |
GFS:A07281 | eukaryotic translation initiation factor 2C, 4; Anti | ANTIBODIES | n/a |
GFS:P07281 | eukaryotic translation initiation factor 2C, 4; Protien | Protien | n/a |