| Symbol: Name: ID: |
ELMO3 engulfment and cell motility 3 GFS:6372 |
| Gene name: | ELMO3 |
| Chromosome: | 16q22.1 |
| Previous Symbols: | |
| Previous Names: | engulfment and cell motility 3 (ced-12 homolog, C. elegans) |
| Aliases: | FLJ13824, CED12, ELMO-3, CED-12 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2679007 | Rat Genome Database ID: | RGD:1304734 |
| HGNC ID: | HGNC:17289 | RefSeq IDs: | NM_024712 |
| Entrez Gene ID: | 79767 | Ensembl Gene ID: | ENSG00000102890 |
| VEGA IDs: | OTTHUMG00000133570 | UniProt ID: | Q96BJ8 |
| UCSC ID: | uc002esa.2 | OMIM ID: | 606422 |
| Pubmed: | PMID11595183 | ||
| CCDS IDs: | CCDSCCDS10833.2 | ||
The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008].
Function: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).
Products for ELMO3 gene
| Catalog | Product Name | Application | Company |
| GFS:E06372 | engulfment and cell motility 3; ELISA kit | ELISA | n/a |
| GFS:A06372 | engulfment and cell motility 3; Anti | ANTIBODIES | n/a |
| GFS:P06372 | engulfment and cell motility 3; Protien | Protien | n/a |
