| Symbol: Name: ID: |
ELMO2 engulfment and cell motility 2 GFS:6320 |
| Gene name: | ELMO2 |
| Chromosome: | 20q13 |
| Previous Symbols: | |
| Previous Names: | engulfment and cell motility 2 (ced-12 homolog, C. elegans) |
| Aliases: | CED12, ELMO-2, CED-12, KIAA1834, FLJ11656 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:2153045 | Rat Genome Database ID: | RGD:1305784 |
| HGNC ID: | HGNC:17233 | RefSeq IDs: | NM_133171 |
| Entrez Gene ID: | 63916 | Ensembl Gene ID: | ENSG00000062598 |
| VEGA IDs: | OTTHUMG00000033070 | UniProt ID: | Q96JJ3 |
| UCSC ID: | uc002xru.1 | OMIM ID: | 606421 |
| Pubmed: | PMID11595183 | ||
| CCDS IDs: | CCDSCCDS13398.1 | ||
Engulfment and cell motility protein 2 is a protein that in humans is encoded by the ELMO2 gene.
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
Function: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Products for ELMO2 gene
| Catalog | Product Name | Application | Company |
| GFS:E06320 | engulfment and cell motility 2; ELISA kit | ELISA | n/a |
| GFS:A06320 | engulfment and cell motility 2; Anti | ANTIBODIES | n/a |
| GFS:P06320 | engulfment and cell motility 2; Protien | Protien | n/a |
