Symbol: Name: ID: |
DUSP16 dual specificity phosphatase 16 GFS:6809 |
Gene name: | DUSP16 |
Chromosome: | 12p13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MKP-7, KIAA1700, MKP7 |
Name Aliases: | MAPK phosphatase-7 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1917936 | Rat Genome Database ID: | RGD:1310721 |
HGNC ID: | HGNC:17909 | RefSeq IDs: | NM_030640 |
Entrez Gene ID: | 80824 | Ensembl Gene ID: | ENSG00000111266 |
VEGA IDs: | UniProt ID: | Q9BY84 | |
UCSC ID: | uc001rao.1 | OMIM ID: | 607175 |
Pubmed: | PMID11359773 PMID 11489891 PMID 15888437 | ||
CCDS IDs: | CCDSCCDS8650.1 |
Dual specificity protein phosphatase 16 is an enzyme that in humans is encoded by the DUSP16 gene.
This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.
Products for DUSP16 gene
Catalog | Product Name | Application | Company |
GFS:E06809 | dual specificity phosphatase 16; ELISA kit | ELISA | n/a |
GFS:A06809 | dual specificity phosphatase 16; Anti | ANTIBODIES | n/a |
GFS:P06809 | dual specificity phosphatase 16; Protien | Protien | n/a |