Symbol: Name: ID: |
DUSP14 dual specificity phosphatase 14 GFS:6098 |
Gene name: | DUSP14 |
Chromosome: | 17q12 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MKP-L, MKP6 |
Name Aliases: | MKP-1 like protein tyrosine phosphatase |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1927168 | Rat Genome Database ID: | RGD:1590821 |
HGNC ID: | HGNC:17007 | RefSeq IDs: | NM_007026 |
Entrez Gene ID: | 11072 | Ensembl Gene ID: | ENSG00000161326 |
VEGA IDs: | OTTHUMG00000133061 | UniProt ID: | O95147 |
UCSC ID: | uc002hnx.2 | OMIM ID: | 606618 |
Pubmed: | PMID11123293 | ||
CCDS IDs: | CCDSCCDS11320.1 |
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009].
Function: Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases.
Products for DUSP14 gene
Catalog | Product Name | Application | Company |
GFS:E06098 | dual specificity phosphatase 14; ELISA kit | ELISA | n/a |
GFS:A06098 | dual specificity phosphatase 14; Anti | ANTIBODIES | n/a |
GFS:P06098 | dual specificity phosphatase 14; Protien | Protien | n/a |