Symbol: Name: ID: |
C8B complement component 8, beta polypeptide GFS:3083 |
Gene name: | C8B |
Chromosome: | 1p36.2-p22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88236 | Rat Genome Database ID: | RGD:2239 |
HGNC ID: | HGNC:1353 | RefSeq IDs: | NM_000066 |
Entrez Gene ID: | 732 | Ensembl Gene ID: | |
VEGA IDs: | OTTHUMG00000008305 | UniProt ID: | P07358 |
UCSC ID: | uc001cyp.2 | OMIM ID: | 120960 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS30730.1 |
C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Products for C8B gene
Catalog | Product Name | Application | Company |
GFS:E03083 | complement component 8, beta polypeptide; ELISA kit | ELISA | n/a |
GFS:A03083 | complement component 8, beta polypeptide; Anti | ANTIBODIES | n/a |
GFS:P03083 | complement component 8, beta polypeptide; Protien | Protien | n/a |