Symbol: Name: ID: |
C9orf3 chromosome 9 open reading frame 3 GFS:3154 |
Gene name: | C9orf3 |
Chromosome: | 9q22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | C90RF3, FLJ14675, APO, AOPEP, AP-O |
Name Aliases: | aminopeptidase O |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919311 | Rat Genome Database ID: | RGD:1309592 |
HGNC ID: | HGNC:1361 | RefSeq IDs: | NM_001193329 |
Entrez Gene ID: | 84909 | Ensembl Gene ID: | ENSG00000148120 |
VEGA IDs: | OTTHUMG00000020276 | UniProt ID: | Q8N6M6 |
UCSC ID: | uc004auy.2 | OMIM ID: | |
Pubmed: | PMID12477932 | ||
CCDS IDs: | CCDSCCDS6713.1 |
This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. This protein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010].
Function: Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart.
Products for C9orf3 gene
Catalog | Product Name | Application | Company |
GFS:E03154 | chromosome 9 open reading frame 3; ELISA kit | ELISA | n/a |
GFS:A03154 | chromosome 9 open reading frame 3; Anti | ANTIBODIES | n/a |
GFS:P03154 | chromosome 9 open reading frame 3; Protien | Protien | n/a |