Symbol: Name: ID: |
XCR1 chemokine (C motif) receptor 1 GFS:5377 |
Gene name: | XCR1 |
Chromosome: | 3p21.3-p21.1 |
Previous Symbols: | GPR5, CCXCR1 |
Previous Names: | chemokine (C motif) XC receptor 1 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1346338 | Rat Genome Database ID: | RGD:1311480 |
HGNC ID: | HGNC:1625 | RefSeq IDs: | NM_001024644 |
Entrez Gene ID: | 2829 | Ensembl Gene ID: | ENSG00000173578 |
VEGA IDs: | OTTHUMG00000133449 | UniProt ID: | P46094 |
UCSC ID: | uc003cpf.2 | OMIM ID: | 600552 |
Pubmed: | PMID7832990 PMID 10400311 | ||
CCDS IDs: | CCDSCCDS2736.1 |
The "C" sub-family of chemokine receptors contains only one member: XCR1, the receptor for XCL1 and XCL2 (or lymphotactin-1 and -2).
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level.
Products for XCR1 gene
Catalog | Product Name | Application | Company |
GFS:E05377 | chemokine (C motif) receptor 1; ELISA kit | ELISA | n/a |
GFS:A05377 | chemokine (C motif) receptor 1; Anti | ANTIBODIES | n/a |
GFS:P05377 | chemokine (C motif) receptor 1; Protien | Protien | n/a |