Symbol: Name: ID: |
CXCR5 chemokine (C-X-C motif) receptor 5 GFS:523 |
Gene name: | CXCR5 |
Chromosome: | 11q23.3 |
Previous Symbols: | BLR1 |
Previous Names: | Burkitt lymphoma receptor 1, GTP-binding protein, "Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)" |
Aliases: | MDR15, CD185 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:103567 | Rat Genome Database ID: | RGD:62010 |
HGNC ID: | HGNC:1060 | RefSeq IDs: | NM_001716 |
Entrez Gene ID: | 643 | Ensembl Gene ID: | ENSG00000160683 |
VEGA IDs: | UniProt ID: | P32302 | |
UCSC ID: | uc001pue.3 | OMIM ID: | 601613 |
Pubmed: | PMID1425907 | ||
CCDS IDs: | CCDSCCDS8402.1 |
CXCR5 was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist. [provided by RefSeq].
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation
Products for CXCR5 gene
Catalog | Product Name | Application | Company |
GFS:E00523 | chemokine (C-X-C motif) receptor 5; ELISA kit | ELISA | n/a |
GFS:A00523 | chemokine (C-X-C motif) receptor 5; Anti | ANTIBODIES | n/a |
GFS:P00523 | chemokine (C-X-C motif) receptor 5; Protien | Protien | n/a |