Symbol: Name: ID: |
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 GFS:6482 |
Gene name: | CHST12 |
Chromosome: | 7p22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | C4S-2, C4ST2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929064 | Rat Genome Database ID: | RGD:1308214 |
HGNC ID: | HGNC:17423 | RefSeq IDs: | NM_018641 |
Entrez Gene ID: | 55501 | Ensembl Gene ID: | ENSG00000136213 |
VEGA IDs: | OTTHUMG00000023849 | UniProt ID: | Q9NRB3 |
UCSC ID: | uc003smd.2 | OMIM ID: | 610129 |
Pubmed: | PMID10781601 | ||
CCDS IDs: | CCDSCCDS5333.1 |
Carbohydrate sulfotransferase 12 is an enzyme that in humans is encoded by the CHST12 gene.
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011].
Function: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
Products for CHST12 gene
Catalog | Product Name | Application | Company |
GFS:E06482 | carbohydrate (chondroitin 4) sulfotransferase 12; ELISA kit | ELISA | n/a |
GFS:A06482 | carbohydrate (chondroitin 4) sulfotransferase 12; Anti | ANTIBODIES | n/a |
GFS:P06482 | carbohydrate (chondroitin 4) sulfotransferase 12; Protien | Protien | n/a |