Symbol: Name: ID: |
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 GFS:3293 |
Gene name: | CHST7 |
Chromosome: | Xp11.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | C6ST-2, C6ST2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891767 | Rat Genome Database ID: | RGD:1303028 |
HGNC ID: | HGNC:13817 | RefSeq IDs: | NM_019886 |
Entrez Gene ID: | 56548 | Ensembl Gene ID: | ENSG00000147119 |
VEGA IDs: | OTTHUMG00000021423 | UniProt ID: | Q9NS84 |
UCSC ID: | uc004dgt.2 | OMIM ID: | 300375 |
Pubmed: | PMID10781596 | ||
CCDS IDs: | CCDSCCDS14268.1 |
Carbohydrate sulfotransferase 7 is an enzyme that in humans is encoded by the CHST7 gene.
This gene belongs to the sulfotransferase gene family. Sulfotransferases generate sulfated glycosaminoglycan (GAG) moities during chondroitin sulfate biosynthesis. They create considerable structural diversity among chondroitin sulfates by transferring sulfate with remarkable specificity for the underlying oligosaccharide substrate. This gene product mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of this gene family may be an important determinant of sulfated GAGs expression and the associated function of chondroitin sulfates as regulators of many biologic processes. This gene is part of a gene cluster on chromosome Xp11.23. [provided by RefSeq, Jul 2008].
Function: Catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc.
Products for CHST7 gene
Catalog | Product Name | Application | Company |
GFS:E03293 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7; ELISA kit | ELISA | n/a |
GFS:A03293 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7; Anti | ANTIBODIES | n/a |
GFS:P03293 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7; Protien | Protien | n/a |