Symbol: Name: ID: |
CAMK2B calcium/calmodulin-dependent protein kinase II beta GFS:3909 |
Gene name: | CAMK2B |
Chromosome: | 7p14.3-p14.1 |
Previous Symbols: | CAMKB |
Previous Names: | calcium/calmodulin-dependent protein kinase (CaM kinase) II beta |
Aliases: | CAM2, CAMK2 |
Name Aliases: | CaM-kinase II beta chain, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88257 | Rat Genome Database ID: | RGD:2262 |
HGNC ID: | HGNC:1461 | RefSeq IDs: | NM_001220 |
Entrez Gene ID: | 816 | Ensembl Gene ID: | ENSG00000058404 |
VEGA IDs: | OTTHUMG00000023491 | UniProt ID: | Q13554 |
UCSC ID: | uc003tkq.2 | OMIM ID: | 607707 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS5483.1 CCDS CCDS5484.1 CCDS CCDS5485.1 CCDS CCDS5486.1 CCDS CCDS5487.1 CCDS CCDS5488.1 CCDS CCDS5489.1 CCDS CCDS43573.1 |
Calcium/calmodulin-dependent protein kinase type II beta chain is an enzyme that in humans is encoded by the CAMK2B gene.
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Function: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
Products for CAMK2B gene
Catalog | Product Name | Application | Company |
GFS:E03909 | calcium/calmodulin-dependent protein kinase II beta; ELISA kit | ELISA | n/a |
GFS:A03909 | calcium/calmodulin-dependent protein kinase II beta; Anti | ANTIBODIES | n/a |
GFS:P03909 | calcium/calmodulin-dependent protein kinase II beta; Protien | Protien | n/a |