Symbol: Name: ID: |
CDH20 cadherin 20, type 2 GFS:6572 |
Gene name: | CDH20 |
Chromosome: | 18q21.33 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CDH7L3, Cdh7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1346069 | Rat Genome Database ID: | RGD:1305438 |
HGNC ID: | HGNC:1760 | RefSeq IDs: | NM_031891 |
Entrez Gene ID: | 28316 | Ensembl Gene ID: | ENSG00000101542 |
VEGA IDs: | OTTHUMG00000132768 | UniProt ID: | Q9HBT6 |
UCSC ID: | uc010dps.1 | OMIM ID: | 605807 |
Pubmed: | PMID10995570 | ||
CCDS IDs: | CCDSCCDS11977.1 |
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008].
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Products for CDH20 gene
Catalog | Product Name | Application | Company |
GFS:E06572 | cadherin 20, type 2; ELISA kit | ELISA | n/a |
GFS:A06572 | cadherin 20, type 2; Anti | ANTIBODIES | n/a |
GFS:P06572 | cadherin 20, type 2; Protien | Protien | n/a |