Symbol: Name: ID: |
PCDHB16 protocadherin beta 16 GFS:3860 |
Gene name: | PCDHB16 |
Chromosome: | 5q31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PCDHB8a, PCDH3X, KIAA1621, PCDH-BETA16, ME1 |
Name Aliases: | cadherin ME1, |
Locus Type: | protocadherin |
Mouse Genome Database ID: | MGI:2136754 | Rat Genome Database ID: | RGD:1549775 |
HGNC ID: | HGNC:14546 | RefSeq IDs: | NM_020957 |
Entrez Gene ID: | 57717 | Ensembl Gene ID: | ENSG00000196963 |
VEGA IDs: | OTTHUMG00000129605 | UniProt ID: | Q9NRJ7 |
UCSC ID: | uc003liv.2 | OMIM ID: | 606345 |
Pubmed: | PMID11230163 PMID 11322959 | ||
CCDS IDs: | CCDSCCDS4251.1 |
Protocadherin beta-16 is a protein that in humans is encoded by the PCDHB16 gene.
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008].
Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Products for PCDHB16 gene
Catalog | Product Name | Application | Company |
GFS:E03860 | protocadherin beta 16; ELISA kit | ELISA | n/a |
GFS:A03860 | protocadherin beta 16; Anti | ANTIBODIES | n/a |
GFS:P03860 | protocadherin beta 16; Protien | Protien | n/a |