Symbol: Name: ID: |
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) GFS:6526 |
Gene name: | CDH11 |
Chromosome: | 16q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | OB, CAD11 |
Name Aliases: | OB-Cadherin |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:99217 | Rat Genome Database ID: | RGD:619742 |
HGNC ID: | HGNC:1750 | RefSeq IDs: | NM_001797 |
Entrez Gene ID: | 1009 | Ensembl Gene ID: | ENSG00000140937 |
VEGA IDs: | OTTHUMG00000137494 | UniProt ID: | P55287 |
UCSC ID: | uc002eoi.2 | OMIM ID: | 600023 |
Pubmed: | PMID9615235 | ||
CCDS IDs: | CCDSCCDS10803.1 |
Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Products for CDH11 gene
Catalog | Product Name | Application | Company |
GFS:E06526 | cadherin 11, type 2, OB-cadherin (osteoblast); ELISA kit | ELISA | n/a |
GFS:A06526 | cadherin 11, type 2, OB-cadherin (osteoblast); Anti | ANTIBODIES | n/a |
GFS:P06526 | cadherin 11, type 2, OB-cadherin (osteoblast); Protien | Protien | n/a |