Symbol: Name: ID: |
CDH10 cadherin 10, type 2 (T2-cadherin) GFS:6517 |
Gene name: | CDH10 |
Chromosome: | 5p14.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107436 | Rat Genome Database ID: | RGD:619741 |
HGNC ID: | HGNC:1749 | RefSeq IDs: | NM_001190450 |
Entrez Gene ID: | 1008 | Ensembl Gene ID: | ENSG00000040731 |
VEGA IDs: | OTTHUMG00000090667 | UniProt ID: | Q9Y6N8 |
UCSC ID: | uc003jgr.1 | OMIM ID: | 604555 |
Pubmed: | PMID2059658 | ||
CCDS IDs: | CCDSCCDS3892.1 |
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. [provided by RefSeq, Jan 2011].
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Products for CDH10 gene
Catalog | Product Name | Application | Company |
GFS:E06517 | cadherin 10, type 2 (T2-cadherin); ELISA kit | ELISA | n/a |
GFS:A06517 | cadherin 10, type 2 (T2-cadherin); Anti | ANTIBODIES | n/a |
GFS:P06517 | cadherin 10, type 2 (T2-cadherin); Protien | Protien | n/a |