Symbol: Name: ID: |
CDH19 cadherin 19, type 2 GFS:6559 |
Gene name: | CDH19 |
Chromosome: | 18q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CDH7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3588198 | Rat Genome Database ID: | RGD:1307169 |
HGNC ID: | HGNC:1758 | RefSeq IDs: | NM_021153 |
Entrez Gene ID: | 28513 | Ensembl Gene ID: | ENSG00000071991 |
VEGA IDs: | OTTHUMG00000132802 | UniProt ID: | Q9H159 |
UCSC ID: | uc002lkc.1 | OMIM ID: | 603016 |
Pubmed: | PMID10995570 | ||
CCDS IDs: | CCDSCCDS11994.1 |
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008].
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Products for CDH19 gene
Catalog | Product Name | Application | Company |
GFS:E06559 | cadherin 19, type 2; ELISA kit | ELISA | n/a |
GFS:A06559 | cadherin 19, type 2; Anti | ANTIBODIES | n/a |
GFS:P06559 | cadherin 19, type 2; Protien | Protien | n/a |