Symbol: Name: ID: |
CDH18 cadherin 18, type 2 GFS:6554 |
Gene name: | CDH18 |
Chromosome: | 5p14.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CDH14, EY-CADHERIN |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1344366 | Rat Genome Database ID: | |
HGNC ID: | HGNC:1757 | RefSeq IDs: | NM_001167667 |
Entrez Gene ID: | 1016 | Ensembl Gene ID: | ENSG00000145526 |
VEGA IDs: | OTTHUMG00000090578 | UniProt ID: | Q13634 |
UCSC ID: | uc003jgc.2 | OMIM ID: | 603019 |
Pubmed: | PMID9030594 PMID 10191097 | ||
CCDS IDs: | CCDSCCDS3889.1 |
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008].
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Products for CDH18 gene
Catalog | Product Name | Application | Company |
GFS:E06554 | cadherin 18, type 2; ELISA kit | ELISA | n/a |
GFS:A06554 | cadherin 18, type 2; Anti | ANTIBODIES | n/a |
GFS:P06554 | cadherin 18, type 2; Protien | Protien | n/a |